Design, synthesis, molecular docking, and antimicrobial evaluation of hybrid peptides incorporating unnatural amino acids with enhanced hydrophobic sidechains | Synapse
February 27, 2026Open Access
Design, synthesis, molecular docking, and antimicrobial evaluation of hybrid peptides incorporating unnatural amino acids with enhanced hydrophobic sidechains
Key Points
The aim is to design and evaluate hybrid peptides that incorporate unnatural amino acids with enhanced hydrophobic properties for antimicrobial application.
Synthesis of hybrid peptides with unnatural amino acids
Molecular docking to predict interactions with target sites
Evaluation of antimicrobial activity against multidrug-resistant pathogens