Characterisation of the Novel HLA-B*37:112N Allele by Next-Generation Sequencing.

Key Points

• This research aims to characterize the novel HLA-B*37:112N allele through sequencing techniques.
• Utilized next-generation sequencing to analyze the allele.
• Focused on codon 262 in exon 4 for nucleotide differences.
• Compared HLA-B*37:112N to HLA-B*37:01:01:01.
• Identified a single nucleotide substitution at codon 262.
• Confirmed the presence of the novel allele HLA-B*37:112N.