What question did this study set out to answer?

The study aims to assess the management, outcomes, and mortality risk factors for cardiogenic shock related to acute myocardial infarction.

February 28, 2026Open Access

Cardiogenic shock in the course of myocardial infarction: the results of the Shock-POL registry

Key Result

In patients with AMI-related cardiogenic shock, in-hospital mortality was 47.5%, with non-STEMI, high lactates, older age, and no antibiotic need predicting death.

Key Points

The study aims to assess the management, outcomes, and mortality risk factors for cardiogenic shock related to acute myocardial infarction.
Conducted a snap-shot registry across 9 cardiology centers in Poland.
Included patients with prolonged hypotension and signs of hypoperfusion after acute myocardial infarction.
Measured in-hospital mortality as the primary endpoint.
141 patients were evaluated, with a mean age of 69.2 years and a majority being male (72.3%).
In-hospital mortality rate was 47.5%, and 30-day mortality was 51.8%.
Non-ST-elevation myocardial infarction, elevated lactates, and age were identified as independent predictors of in-hospital mortality.

Structured PICO

Population

141 patients with acute myocardial infarction (AMI) complicated by cardiogenic shock (defined as prolonged >20 min hypotension with signs of peripheral hypoperfusion) qualified for urgent coronary angiography, mean age 69.2, 72.3% men, hospitalized across 9 cardiology centers in Poland.

Outcome

In-hospital mortalityhard clinical

In a contemporary Polish registry, AMI-related cardiogenic shock remains associated with a high in-hospital mortality rate of 47.5%, with older age, NSTEMI presentation, and elevated lactates serving as independent predictors of death.

Main Result

Absolute Event Rate: 0% vs 0%

Abstract

Abstract Aims Cardiogenic shock (CS) represents an ominous complication of acute myocardial infarction (AMI) with mortality rate exceeding 50%. The aim of the study was to evaluate current management, outcomes and risk factors of mortality of AMI-related CS. Methods This snap-shot registry evaluated all patients with AMI-related CS hospitalized in 9 cardiology centers across Poland between January and December 2023. The inclusion criteria involved CS defined as prolonged (20 min) hypotension with signs of peripheral hypoperfusion and diagnosis of AMI qualified for urgent coronary angiography. The primary endpoint was in-hospital mortality. Results The study comprised 141 patients (72.3% men; mean age was 69.2 14 years). The majority of patients were in Society for Cardiovascular Angiography and Interventions class C (n=71,50.4%), followed by class D (n=46,32.6%) and class E (n=24,17.0%). Percutaneous coronary intervention was performed in 133 cases (94.3%) while coronary artery bypass graft in 5 (3.5%). Mechanical circulatory support (MCS) was used in 33 patients (23.4%) and involved intra-aortic balloon pump (n=26,18.4%), Impella CP (n=6,4.3%), Impella 5.5 (n=2,1.4%) and veno-arterial extracorporeal membrane oxygenation (n=10,7.1%). In-hospital mortality rate was 47.5% (n=67), while 30-day mortality was 51.8% (n=73). Cox proportional hazards model showed that non-ST-elevation AMI (HR=2.38,95%CI:1.19-4.75), lack of the need for antibiotic therapy (HR=2.61, 95%CI:1.26-5.39), elevated lactates (unit HR per 1 mmol/l=1.19, 95%CI:1.11-1.27) and age (unit HR=1.05; 95%CI:1.02-1.07) were independent predictors of in-hospital mortality. Conclusions Short-term mortality rate of AMI-related CS still amounts to 50%, which advocates in favor of further research evaluating the true role of MCS in this population.