Gastric neuroendocrine tumors are uncommon neoplasms arising from neuroendocrine cells of the gastric mucosa. They are classified into three main clinical types based on underlying etiology. We present the case of a 45-year-old woman with a 6-month history of epigastric discomfort and postprandial fullness. Upper gastrointestinal endoscopy revealed a solitary 1.5 cm polypoid lesion in the gastric fundus. Histopathological evaluation confirmed a well-differentiated Grade 1 gastric neuroendocrine tumor. The patient had no history of autoimmune atrophic gastritis, and serum gastrin was only mildly elevated, supporting a diagnosis of type 3 (sporadic) gastric neuroendocrine tumor. Endoscopic snare polypectomy was performed successfully, and follow-up revealed no recurrence. This case highlights the importance of recognizing type 3 gastric neuroendocrine tumors and reinforces the role of endoscopic resection in selected small, well-differentiated lesions.
Parmar et al. (Wed,) studied this question.