What question did this study set out to answer?

This trial aims to assess whether suction mini-PCNL is as effective as standard PCNL for managing 2-4 cm kidney stones.

February 28, 2026Open Access

Suction mini-percutaneous nephrolithotomy versus standard percutaneous nephrolithotomy for the management of 2–4 cm kidney stones: study protocol for an international, multicenter, parallel-group, noninferiority, randomized controlled trial

Key Points

This trial aims to assess whether suction mini-PCNL is as effective as standard PCNL for managing 2-4 cm kidney stones.
International multicenter design
Parallel-group randomization
Randomized controlled trial format
Focus on 2-4 cm kidney stones
Aims to provide high-level evidence for noninferiority
Evaluation of patient outcomes and complications expected.

Abstract

The aim of this trial is to generate high-level evidence regarding the noninferiority of suction mini-PCNL compared to standard PCNL for 2-4 cm renal stones. The trial is registered on ClinicalTrials.gov as NCT05088213.

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Suction mini-percutaneous nephrolithotomy versus standard percutaneous nephrolithotomy for the management of 2–4 cm kidney stones: study protocol for an international, multicenter, parallel-group, noninferiority, randomized controlled trial

Key Points

Abstract

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