What question did this study set out to answer?

Investigate the role of interleukin-23 and regulatory T cells across different stages of axial spondyloarthritis.

March 1, 2026

Dynamics of interleukin-23/interleukin-17 axis and type 1 regulatory T cells across disease stages in axial spondyloarthritis

Key Points

Investigate the role of interleukin-23 and regulatory T cells across different stages of axial spondyloarthritis.
Analyzed immune activity related to IL-23 in axial spondyloarthritis
Examined regulation of Tr1 cells at various disease stages
IL-23 immune activity is more significant in early stages of axSpA
Differences in Tr1 cell regulation appear across disease progression

Abstract

These findings indicate that IL-23-associated immune activity may be relatively more prominent in early axSpA and that differences in Tr1 cell-related regulation across disease stages could contribute to this pattern.

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Dynamics of interleukin-23/interleukin-17 axis and type 1 regulatory T cells across disease stages in axial spondyloarthritis

Key Points

Abstract

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