Do we worry too much about polysorbate degradation? An industry-wide perspective with real-life case studies

Key Points

• Polysorbate degradation may present safety concerns that warrant careful consideration in industrial settings.
• Key case studies illustrate various degradation scenarios, emphasizing the need for robust testing protocols.
• Assessment of chemical stability reveals that certain degradation pathways are more commonly observed than others.
• Understanding polysorbate degradation can enhance product safety, but comprehensive evaluations are still required.