STUDY OF GENETIC ASSOCIATION BETWEEN the rs1799817 POLYMORPHISM OF THE INSULIN RECEPTOR GENE and THE DEVELOPMENT OF TYPE 2 DIABETES MELLITUS

Key Points

• Type 2 diabetes develops due to defects in the insulin signaling pathway, leading to elevated blood glucose levels.
• The rs1799817 polymorphism in the insulin receptor gene has a notable genetic association with type 2 diabetes development.
• Analysis of genetic factors reveals the complexity of interactions leading to metabolic disease such as type 2 diabetes.
• Understanding these genetic associations may highlight new interventions for preventing or managing type 2 diabetes.