Combining OCT and OCT angiography improves differentiation of mild cognitive impairment and Alzheimer’s disease

Key Points

• Discriminative performance improved significantly when using both OCT and OCT angiography metrics.
• Integration of these two imaging modalities enhances the detection of structural and vascular changes.
• Assessment of OCT and OCTA measures demonstrates complementary value in identifying cognitive impairment nuances.
• Results highlight the need for integrated imaging approaches for effective diagnosis of Alzheimer's disease.