The study focuses on the preparation of chitosan scaffolds using electrospinning and magneto spinning techniques to develop biomaterials that closely resemble the natural extracellular matrix (ECM) for applications in tissue engineering, drug delivery, and other biomedical fields. Chitosan, a biocompatible biopolymer, supports the healing of both soft and hard connective tissues. Electrospinning and magneto spinning differ in their working principles, resulting in distinct fiber morphologies and structural features. Electrospinning produces non-woven nanofibrous mats, while magneto spinning, a more recent method, enables the formation of aligned or helical microfibers through the incorporation of gold nanoparticles into the chitosan matrix. The scaffolds fabricated by both techniques were analysed using scanning electron microscopy (SEM). SEM results revealed that electro spun chitosan scaffolds exhibited a uniform, randomly oriented nanofiber structure with smooth surface morphology, whereas magneto-spun scaffolds showed thicker, well-aligned helical fibres with improved inter-fiber connectivity. These distinct microstructural characteristics suggest potential differences in mechanical properties and cellular interactions, highlighting the suitability of each scaffold type for specific biomedical applications.
Rao et al. (Wed,) studied this question.