Erianin induces ferroptosis in ovarian cancer cells by upregulating PDP2 and activating the JNK signaling pathway

Key Points

• Erianin induces ferroptosis in ovarian cancer cells, promoting cell death and reducing proliferation.
• Cell viability decreased by over 50% after treatment with erianin in vitro within 24 hours.
• Functional assays demonstrate activation of the JNK signaling pathway through PDP2 upregulation.
• These findings highlight the potential of erianin as a novel therapeutic agent in overcoming ovarian cancer.