March 3, 2026

Model for End-Stage Liver Disease-Lactate and Lactate Clearance in Critically Ill Cirrhosis Patients With Sepsis

Key Points

Early reduction in lactate levels by one-third correlates with 30-day mortality in cirrhosis patients.
Combining MELD-LA and lactate clearance enhances risk stratification for this patient group.
Assessment relies on monitoring lactate levels to inform clinical management in the ICU.
Understanding these markers may improve outcomes for critically ill patients suffering from sepsis.

Abstract

Early reduction in initial LA by one-third predicts 30-day mortality and may indicate treatment response in cirrhosis patients with sepsis in the ICU. Combining MELD-LA and LA clearance early enables better risk stratification and informs management.

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Cite This Study

Shabbir et al. (Tue,) studied this question.

synapsesocial.com/papers/69a75b36c6e9836116a22224 https://doi.org/https://doi.org/10.14309/ajg.0000000000003934

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