Under the current conditions of poultry intensification, specialists are required to implement effective and safe solutions rapidly to preserve bird health and improve the quality. One promising approach is the use of bioactive compounds from marine seaweeds, which can modulate the immune response and enhance intestinal barrier functions. Marine macroalgae are a valuable source of vitamins (A, B, C, D, E), minerals (Fe, Ca, Mg, I, Se), amino acids, and antioxidants, all essential for maintaining physiological processes and overall health in poultry. Of particular importance are the sulfated polysaccharides of macroalgal cell walls, which possess a unique structure and a broad spectrum of biological activities, including anticoagulant, antiviral, antibacterial, antitumor, enteroprotective, antiproliferative, and immunomodulatory effects.Based on innovative technologies developed by Olmix Group (France), the feed additive "Algimun" was formulated. Its main active components are sulfated polysaccharides extracted from marine seaweeds: MSP®IMMUNITY (green algae extract, which modulates both innate and adaptive immune responses) and MSP®BARRIER (red algae extract, which strengthens the barrier function of the intestinal epithelium). The synergistic action of these extracts reduces pathogen translocation across the intestinal epithelium and enhances the first line of immune defense.Experimental studies demonstrated that "Algimun" exhibits pronounced virucidal activity. Using an express assay, the absence of lysis zones at sites treated with the mixture and bacteriophage was confirmed. In ovo experiments with chicken embryos showed a reduction in mortality caused by Newcastle disease virus to 14%. Additionally, "Algimun" displayed antimicrobial activity: the inhibition zones for Staphylococcus aureus-209 and Escherichia coli measured 21 mm and 24 mm, respectively, which is comparable to the effects of standard antibiotics (ciprofloxacin and amikacin).Overall, these results support the potential application of "Algimun" in poultry production as a tool for enhancing natural resistance and protecting birds from pathogenic agents.
AVDOSIEVA et al. (Tue,) studied this question.