Metabolic shifts occur as development progresses to meet changing energy demands and sources. In a recent study, Elvira Mass and colleagues show that Kupffer cells, tissue-resident macrophages in the liver, are crucial for one of these metabolic switches at birth. To learn more about the work, we spoke to Nikola Makdissi and Daria Hirschmann, co-first authors of the study from the Developmental Biology of the Immune System, Life & Medical Sciences (LIMES) Institute, Germany.
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