March 3, 2026Open Access

Case Report: Re-irradiation of out-of-field recurrence of malignant phyllodes tumors of the breast after adjuvant radiotherapy

Key Points

Re-irradiation showed promise in managing out-of-field recurrence of malignant phyllodes tumors.
Adjuvant radiotherapy can reduce the risk of recurrence in breast tumors of this type with careful selection.
Protocol development is needed for optimal radiotherapy dose fractionation and comparison of vital targets.
Further exploration into the safety of re-irradiation practices for this cancer type is warranted.

Abstract

This case highlights the potential role of adjuvant RT in reducing recurrence and the feasibility of carefully selected re-irradiation for recurrent MPTs. Prospective studies are needed to define optimal target volume of radiotherapy, dose fractionation, and the safety of re-irradiation.

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Cite This Study

Li et al. (Thu,) studied this question.

synapsesocial.com/papers/69a75c2ac6e9836116a24b85 https://doi.org/https://doi.org/10.3389/fonc.2026.1694960

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