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Segmental vitiligo: A distinct entity with unique pathogenesis and clinical implications | Synapse
March 3, 2026
Segmental vitiligo: A distinct entity with unique pathogenesis and clinical implications
NS
Naiting Shen
Fudan University
QF
Qinyi Fang
YX
Yijie Xuan
Fudan University
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Key Points
Segmental vitiligo presents with unique clinical features and requires distinct considerations for management, compared to generalized cases.
Initial findings indicate that segmental vitiligo's pathogenesis may involve an autoimmune response, differing from other forms of vitiligo.
Assessment using clinical records shows that melanocyte depletion is a significant factor in the manifestation of segmental vitiligo.
Understanding the specific pathogenesis of segmental vitiligo may lead to tailored therapeutic strategies for affected individuals.
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Shen et al. (Thu,) studied this question.
synapsesocial.com/papers/69a75c83c6e9836116a25738
https://doi.org/https://doi.org/10.1016/j.jid.2025.12.009
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