Mechanisms and safety evaluation of stir-fried atractylodis macrocephalae rhizoma with aurantii fructus in the treatment of inflammatory bowel disease: a study based on organ-on-a-chip model

Key Points

• Active components in stir-fried atractylodis macrocephalae rhizoma show promise in treating inflammatory bowel disease.
• Safety assessment reveals positive outcomes in organ-on-a-chip models, indicating reliability of findings.
• Evaluation of mechanisms highlights the therapeutic potential of the herbal remedy in gastrointestinal conditions.
• Further research on this model could enable novel treatment approaches for inflammatory bowel disease.