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A multicentre evaluation of metagenomic sequencing for pathogen detection in central nervous system infections | Synapse
March 3, 2026
A multicentre evaluation of metagenomic sequencing for pathogen detection in central nervous system infections
JW
Jiali Wang
YM
Yu Ma
XS
Xiankun Shi
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Key Points
Pathogen detection increased significantly with metagenomic sequencing, enhancing diagnostic capabilities.
The study observed a 30% higher detection rate of pathogens compared to traditional methods across multiple centers.
Multicentre evaluation analyzed diverse CNS infections and compared outcomes for better understanding.
Improved pathogen identification potentially leads to more targeted and effective treatments for CNS infections.
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Wang et al. (Thu,) studied this question.
synapsesocial.com/papers/69a75cbec6e9836116a25de3
https://doi.org/https://doi.org/10.1016/j.cmi.2026.01.015