Deciphering the regulatory landscape of enhancer RNAs in health and disease

Key Points

• Enhancer RNAs play a crucial role in gene regulation, affecting various biological processes and conditions.
• Key evidence indicates that most gene regulatory elements are also active as enhancer RNAs, which enhances gene expression.
• This analysis utilizes molecular pathways to investigate the influence of transcription factors on enhancer RNAs in different contexts.
• Understanding enhancer RNAs may enable new therapeutic strategies in treating diseases related to gene regulation dynamics.