March 3, 2026Open Access

Dahuang gancao dandelion decoction regulates intestinal flora and inhibits NF-κB/ARA signaling pathway to alleviate ulcerative colitis

Key Points

Moderation of gut microbiota leads to improved outcomes in ulcerative colitis.
The NF-κB/ARA signaling pathway is effectively inhibited by Dahuang gancao dandelion decoction.
DGD-D enhances intestinal barrier function while regulating intestinal metabolites efficiently.
This study suggests that TCM-based treatments could offer new strategies against ulcerative colitis.

Abstract

DGD-D is a viable TCM-based treatment for UC since it improves DSS-induced UC by modifying gut microbiota and intestinal metabolites, reestablishing intestinal barrier function, and blocking the NF-κB/ARA pathway.

Dahuang gancao dandelion decoction regulates intestinal flora and inhibits NF-κB/ARA signaling pathway to alleviate ulcerative colitis

Key Points

Abstract

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