X-intNMF: a cross- and intra-omics regularized NMF framework for multi-omics integration

Key Points

• Integration of multi-omics data is achieved through a novel regularized non-negative matrix factorization (NMF) framework.
• The framework allows for both cross-omics and intra-omics integration for improved analysis and interpretation.
• Publicly available source code and datasets support the integration process, facilitating further research and application.
• This method may enable more comprehensive biological insights from complex omics datasets, enhancing data utility.