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Genomic landscape of stage 0–IA lung adenocarcinoma identified by on-site reflex targeted NGS | Synapse
March 3, 2026
Genomic landscape of stage 0–IA lung adenocarcinoma identified by on-site reflex targeted NGS
MI
Marius Ilié
SH
Simon Heeke
The University of Texas MD Anderson Cancer Center
GR
Guylène Rignol
Pfizer (United States)
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Key Points
Stage 0–IA lung adenocarcinoma has a unique genomic landscape, providing essential insights into early disease.
Key evidence shows that targeted next-generation sequencing (NGS) identified specific molecular pathways in 85% of samples.
Analysis of genomic data utilized on-site reflex targeted NGS to detect critical biomarkers for cancer progression.
Highlights the need for further development in early-stage lung cancer diagnostics using advanced genomic techniques.
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Ilié et al. (Thu,) studied this question.
synapsesocial.com/papers/69a75d99c6e9836116a27c5e
https://doi.org/https://doi.org/10.1016/j.lungcan.2026.108943