March 3, 2026Open Access

Sodium selenite promotes apoptosis and augments autophagic flux in cervical cancer cells by activating the YAP-Hippo signaling pathway

Key Points

Apoptosis significantly increases in cervical cancer cells with sodium selenite treatment, enhancing cancer cell death.
Sodium selenite also promotes autophagic flux, facilitating the removal of damaged cellular components and enhancing cell survival.
Activation of the yap-hippo signaling pathway is crucial to the observed effects of sodium selenite on cancer cells.
Future research may further explore sodium selenite’s role in cervical cancer therapy and corresponding molecular mechanisms.

Abstract

SS restrains cervical cancer progression by inducing apoptosis and accelerating autophagosome turnover through activation of the YAP-Hippo axis. These findings highlight SS and YAP-directed modulation in general, as promising avenues for future cervical cancer therapy development.

Sodium selenite promotes apoptosis and augments autophagic flux in cervical cancer cells by activating the YAP-Hippo signaling pathway

Key Points

Abstract

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