Comparative risk of tuberculosis infection with different TNF-α inhibitors in immune-mediated inflammatory diseases: a systematic review and network meta-analysis

Key Points

• Tuberculosis infection risk varies among different TNF-α inhibitors, highlighting critical safety considerations.
• The analysis includes data from 12 studies, emphasizing the importance of monitoring tuberculosis risk when using these drugs.
• Systematic review and network meta-analysis evaluate comparative risks linked to multiple TNF-α inhibitors.
• Understanding these risks aids in choosing effective treatment options with lower tuberculosis infection likelihood.