Association between systemic inflammation and serum cobalt level in patients with metallic implants: Evidence from NHANES 2015–2020

Key Points

• Systemic inflammation correlates with elevated serum cobalt levels in patients with metallic implants, highlighting potential health concerns.
• Among the 2015-2020 NHANES dataset, patients showed significant differences in inflammatory markers correlated with cobalt levels.
• Assessment used serum cobalt measurements alongside immune response markers to determine potential associations.
• Findings suggest that systemic inflammation may be influenced by metal toxicity from implants, indicating a need for continued monitoring.