6-acetyl-1,1,2,4,4,7-hexamethyltetraline (AHTN) induces abnormal macrophage polarization and nuclear lamina remodeling under low-dosage and long-term exposure | Synapse
March 3, 2026
6-acetyl-1,1,2,4,4,7-hexamethyltetraline (AHTN) induces abnormal macrophage polarization and nuclear lamina remodeling under low-dosage and long-term exposure
Key Points
Abnormal macrophage polarization occurs with long-term exposure to AHTN, indicating significant immune system implications.
Exposure to low-dose AHTN for extended periods induces notable nuclear lamina remodeling, affecting cellular structure.
Analysis of cellular responses highlights AHTN's potential role in modulating macrophage behavior and function.
Findings suggest that prolonged AHTN exposure might result in altered immune responses and cellular health.