Efficient solid-phase extraction of quaternary ammonium alkaloids from traditional Chinese medicines on a novel sulfonic acid group functionalized microporous organic network coated SiO2 composite

Key Points

• Extraction efficiency significantly improved using a novel microporous organic network, maximizing yields.
• The method achieved 85-95% recovery rates of quaternary ammonium alkaloids from various traditional Chinese medicines.
• Assessment on traditional Chinese medicines showed that this functionalized method outperforms existing extraction techniques.
• This study highlights the potential for widespread applications in herbal medicine, though further testing is needed across diverse samples.