Root Canal Microbiome in Patients Undergoing Antineoplastic Therapy: A Next-generation Sequencing Study

Key Points

• The analysis indicates significant changes in the root canal microbiome during antineoplastic therapy, with shifts in bacterial diversity observed.
• Key metric includes the alteration of specific bacterial populations identified through next-generation sequencing over the treatment period.
• Observational analysis utilizing next-generation sequencing to evaluate the microbiome structure in patients undergoing antineoplastic therapy.
• Findings highlight the potential interplay between chemotherapy effects and oral health, suggesting further examination is necessary.