In vivo toxicity and safety evaluation of Calcium-Ion functionalized silica nanocomposites in Drosophila melanogaster for biomedical applications

Key Points

• In vivo toxicity was assessed using silica nanocomposites in Drosophila melanogaster, showing significant safety concerns.
• The study documented key metrics of toxicity related to calcium-ion functionalized silica, highlighting potential risks.
• Analysis involved evaluations of physiological responses in Drosophila to assess nanocomposite safety for biomedical use.
• These findings suggest the need for thorough safety assessments before using nanocomposites in medical applications.