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Cutaneous Toxicities of Small Molecules in Targeted Cancer Therapy Part I – Mechanisms of Toxicity | Synapse
March 3, 2026
Cutaneous Toxicities of Small Molecules in Targeted Cancer Therapy Part I – Mechanisms of Toxicity
IN
Ian Nykaza
Memorial Sloan Kettering Cancer Center
BK
Bernice Y. Kwong
Palo Alto University
AG
Allison Gordon
Memorial Sloan Kettering Cancer Center
Key Points
Cutaneous toxicities are linked to the mechanisms of toxicity associated with small molecules.
Understanding these mechanisms is crucial for enhancing the safety profiles of targeted therapies in cancer treatment.
This observational analysis evaluates the role of biomarkers in predicting toxicities from small molecules.
The findings highlight the need for further research to develop preventative strategies for these adverse effects.
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Nykaza et al. (Thu,) studied this question.
synapsesocial.com/papers/69a75e95c6e9836116a29529
https://doi.org/https://doi.org/10.1016/j.jaad.2026.01.061