Population pharmacokinetics of a single bolus of ciprofol in Chinese pediatric patients

Key Points

• Ciprofol clearance and metabolism differ in the pediatric population, indicating tailored treatment approaches may be essential.
• The study established pharmacokinetic parameters including half-life with assessments indicating variability among young patients.
• Analysis of pharmacokinetics provides insights on drug clearance in children for optimizing dosing regimens in clinical settings.
• Tailored dosing models for ciprofol could improve safety and efficacy in pediatric patients, guiding future clinical applications.