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Protocol for intraventricular injection of retinoids and hypothalamic application of viral vectors in the rat and mouse brain | Synapse
March 3, 2026
Open Access
Protocol for intraventricular injection of retinoids and hypothalamic application of viral vectors in the rat and mouse brain
PI
Peter I. Imoesi
CO
Cristian M. Olarte-Sánchez
TK
Tamás Kozicz
Mount Sinai Hospital
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Key Points
Intraventricular injection of retinoids may influence hypothalamic activity, enhancing our understanding of brain signaling pathways.
Primary aim includes assessing the impacts of retinoids and viral vectors in rodent models within a specified timeframe.
Protocol for this intervention details precise methods for delivery and target areas in the brain, focusing on the hypothalamus.
Impacts of this intervention could lead to novel therapeutic insights; further evaluation in future studies is necessary.
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Imoesi et al. (Sat,) studied this question.
synapsesocial.com/papers/69a75ed0c6e9836116a29c21
https://doi.org/https://doi.org/10.1016/j.xpro.2025.104329