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Caspase inhibition in Huntington's disease: A systematic review of therapeutic strategies and neuroprotective potential | Synapse
March 3, 2026
Caspase inhibition in Huntington's disease: A systematic review of therapeutic strategies and neuroprotective potential
MI
Muhammad Ibrahim
AM
Ayesha Mansoor
Key Points
Caspase inhibition indicates potential neuroprotective effects in Huntington's disease, highlighting a promising therapeutic approach.
Review identifies various therapeutic strategies that harness caspase inhibition to mitigate neurodegeneration effects.
Analysis of literature reveals the multifaceted role of caspases in neurodegeneration related to Huntington's disease.
Findings may guide future targeted interventions for Huntington's disease, enhancing patient care and treatment outcomes.
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Ibrahim et al. (Mon,) studied this question.
synapsesocial.com/papers/69a75f61c6e9836116a2ab7d
https://doi.org/https://doi.org/10.1016/j.jns.2025.125285