Positive association between serum uric acid and metabolic dysfunction-associated steatotic liver disease: insights from a Japanese health checkup cohort

Key Points

• Metabolic dysfunction-associated steatotic liver disease is positively associated with serum uric acid levels, indicating higher risk.
• Each 1 mg/dL increase in serum uric acid was linked to a 1.5-fold increase in metabolic dysfunction-associated steatotic liver disease.
• Cohort analysis included data from health checkups of Japanese adults, assessing serum uric acid and metabolic parameters.
• Highlighting the need for further exploration of how serum uric acid could influence liver health and metabolic function.