Ileal microbial and luminal biomarker dysbiosis precede acute cellular rejection following intestinal transplantation

Key Points

• Acute cellular rejection is predicted by ileal microbial dysbiosis, indicating a connection between gut health and transplant success.
• Key biomarkers identified may provide early indicators for rejection, allowing for timely intervention and management.
• Assessment focused on microbial communities and biomarkers in ileal and luminal samples following intestinal transplantation.
• Findings imply that targeting microbial dysbiosis could improve outcomes in patients post-transplant.