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Early Allogeneic Stem Cell Transplant Toxicities in Older Adults Compared to Younger Adults | Synapse
March 3, 2026
Early Allogeneic Stem Cell Transplant Toxicities in Older Adults Compared to Younger Adults
RJ
Reena V Jayani-Kosarzycki
HM
Harvey J. Murff
Vanderbilt University Medical Center
SD
Steven M Devine
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Key Points
Older adults experience a higher incidence of toxicities post-transplant, indicating significant age-related differences in treatment outcomes.
In patients aged 65 and older, 45% reported severe toxicities within the first year after transplantation.
Comparative analysis across different age groups assessed the severity and types of toxicities; younger adults generally had milder reactions.
Understanding these differences in toxicities may lead to improved management strategies and personalized care for elderly patients.
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Jayani-Kosarzycki et al. (Sun,) studied this question.
synapsesocial.com/papers/69a76007c6e9836116a2c70d
https://doi.org/https://doi.org/10.1016/j.jtct.2025.12.664