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Low-Grade Cytokine Release Syndrome Is Common but Clinically Benign in Pediatric Haploidentical Hematopoietic Cell Transplantation | Synapse
March 3, 2026
Low-Grade Cytokine Release Syndrome Is Common but Clinically Benign in Pediatric Haploidentical Hematopoietic Cell Transplantation
WS
W. Andres Vasconez Samaniego
CL
Cristopher Loerke
IS
Irtiza Sheikh
The University of Texas MD Anderson Cancer Center
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Key Points
Cytokine release syndrome is identified as a common occurrence among pediatric patients.
In the observed pediatric population, the release of cytokines remains clinically benign, indicating a more favorable prognosis.
Observation methods were applied to evaluate occurrences during haploidentical hematopoietic cell transplantation procedures.
These findings suggest that while cytokine release syndrome is prevalent, it does not lead to severe complications in children.
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Samaniego et al. (Sun,) studied this question.
synapsesocial.com/papers/69a7600dc6e9836116a2c733
https://doi.org/https://doi.org/10.1016/j.jtct.2025.12.880
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