Physicochemical characterization and clinical evaluation of 3D-printed subdivided tablets of 6-Mercaptopurine with broad dosage variations

Key Points

• Subdivided tablets of 6-mercaptopurine demonstrate varied dosage forms, enhancing patient adherence with personalized therapy.
• The physicochemical characterization shows critical parameters affecting the drug's release profile, vital for therapeutic efficacy.
• Assessment involved rigorous testing of tablet strength, disintegration, and drug release rates to ensure performance consistency.
• This analysis highlights the versatility of 3D-printing technology in pharmaceutical manufacturing, suggesting broader applications.