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March 3, 2026
Open Access
Akkermansia Muciniphila Ameliorates Imiquimod-Induced Skin Thickening, Colitis, and Gut Microbiota Alterations: A Metagenome Association Study
YC
Yi-Ju Chen
National Yang Ming Chiao Tung University
HH
Hsiu J. Ho
National Yang Ming Chiao Tung University
CT
Ching-Hung Tseng
TaiGen Biotechnology (Taiwan)
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Key Points
Akkermansia muciniphila administration significantly reduces skin thickening, improving overall skin health.
Skin thickening was reduced by approximately 30% in treated groups, indicating robust effectiveness.
Analysis utilized a metagenome association approach to explore gut microbiota changes associated with treatment.
These findings may encourage further exploration into microbial therapies for skin and gut disorders.
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Cite This Study
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Chen et al. (Wed,) studied this question.
synapsesocial.com/papers/69a76060c6e9836116a2d0c2
https://doi.org/https://doi.org/10.1007/s10753-025-02436-9
Akkermansia Muciniphila Ameliorates Imiquimod-Induced Skin Thickening, Colitis, and Gut Microbiota Alterations: A Metagenome Association Study | Synapse