Early Diagnosis of Tuberculosis in Allogeneic Hematopoietic Cell Transplant Recipients Using Plasma Microbial Cell-Free DNA Next Generation Sequencing: A Retrospective Case Series | Synapse
March 3, 2026
Early Diagnosis of Tuberculosis in Allogeneic Hematopoietic Cell Transplant Recipients Using Plasma Microbial Cell-Free DNA Next Generation Sequencing: A Retrospective Case Series
Key Points
Tuberculosis diagnosis is significantly improved using plasma microbial cell-free DNA.
Plasma testing demonstrated high sensitivity, potentially aiding early treatment initiation.
Retrospective case series involving hematopoietic cell transplant recipients highlights the method's capability.
This approach may enable timely intervention, crucial in high-risk populations post-transplant.