Idiopathic Post-CAR-T Hypotension: Prevalence and Management with Midodrine and/or Fludrocortisone

Key Points

• Idiopathic hypotension occurs in CAR-T therapy patients, leading to significant management challenges.
• Key findings indicate that midodrine and fludrocortisone provide symptomatic relief in this population.
• Assessment of treatment effects on blood pressure was performed through observational analysis.
• Management of hypotension post-CAR-T remains critical; additional validation in larger cohorts is needed.