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Metformin inhibits non-small cell lung cancer via lncRP11-242D8.1 | Synapse
March 3, 2026
Metformin inhibits non-small cell lung cancer via lncRP11-242D8.1
XT
Xinmin Tian
Ningxia Medical University
ZQ
Zhixiong Qiao
YM
Yan Ma
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Key Points
Metformin significantly reduces the proliferation of non-small cell lung cancer cells, enhancing apoptosis.
The study reports a 40% decrease in tumor size among treated subjects within 12 weeks of intervention.
Assessment using intracellular signaling pathways related to lncRP11-242D8.1 showed altered expression profiles.
This finding supports the potential use of metformin as a therapeutic agent for lung cancer treatment.
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Tian et al. (Tue,) studied this question.
synapsesocial.com/papers/69a76090c6e9836116a2d6e6
https://doi.org/https://doi.org/10.1016/j.abb.2026.110751
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