Application of 3D Cell Culture Techniques in Nanotoxicology: How Far Are We?

Key Points

• 3D cell culture techniques enhance cell viability and proliferation studies, offering more reliable results.
• Cell viability metrics indicate better performance of 3D systems over traditional 2D models in nanotoxicology.
• Observational analysis across multiple experimental setups highlights significant differences in toxicity outcomes with advanced techniques.
• The findings support the need for innovative methodologies in nanotoxicology to better reflect in vivo conditions.