Plecanatide Is Efficacious in Women Aged 18 to 40 Years With IBS-C and Bloating: A Pooled Analysis of Two Phase 3, Randomized, Placebo-Controlled Trials. | Synapse
March 3, 2026
Plecanatide Is Efficacious in Women Aged 18 to 40 Years With IBS-C and Bloating: A Pooled Analysis of Two Phase 3, Randomized, Placebo-Controlled Trials.
Key Points
Plecanatide demonstrates significant efficacy in reducing bloating symptoms among women aged 18 to 40.
In two phase 3 trials, 58% of participants reported symptom improvement after treatment with plecanatide.
Randomized, placebo-controlled trials assessed the effect of plecanatide on bloating in IBS-C patients.
These findings highlight the therapeutic potential of plecanatide for those suffering from IBS-C symptoms.