Primary plasma cell leukemia: consensus definition by the International Myeloma Working Group according to peripheral blood plasma cell percentage

Key Points

• Plasma cell leukemia is defined with an emphasis on blood plasma cell percentage, allowing better disease classification.
• The consensus reached by the International Myeloma Working Group facilitates standardized diagnosis and management of the condition.
• Approach involves defining immunological characteristics and percentage thresholds for diagnosis using peripheral blood samples.
• This consensus may improve clinical outcomes and aid in the treatment of plasma cell leukemia, but external validation is still necessary.