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Quercetin suppresses the proliferation of thyroid cancer cells by reducing the expression level of DPP4 and inhibiting its enzyme activity | Synapse
March 3, 2026
Quercetin suppresses the proliferation of thyroid cancer cells by reducing the expression level of DPP4 and inhibiting its enzyme activity
JX
Jie Xu
China Three Gorges University
JH
Jingyi Huang
Université Claude Bernard Lyon 1
RZ
Rong Zou
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Key Points
Quercetin significantly reduces the proliferation of thyroid cancer cells, suggesting its potential as a treatment.
Inhibition of DPP4 activity by quercetin correlates with decreased cancer cell growth across multiple assays.
Enzyme activity measurements indicate a direct link between quercetin treatment and DPP4 suppression, affecting cell cycle regulation.
These findings highlight quercetin's potential role in thyroid cancer therapy, although clinical outcomes need further exploration.
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Xu et al. (Sat,) studied this question.
synapsesocial.com/papers/69a7612fc6e9836116a2edfc
https://doi.org/https://doi.org/10.1007/s00210-026-05095-1
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