Harnessing soft DNA nanospheres as a superior alternative to hard nanoparticles for boosting DNAzyme-based colorimetric sensing of lead ions

Key Points

• Soft dna nanospheres significantly improve colorimetric sensing of lead ions compared to hard nanoparticles.
• The study found a notable increase in sensitivity, with a reported detection limit decrease by a factor of 2.
• Assessment of dnazyme performance was conducted using a validated sensing platform in controlled conditions.
• Indicates a need for further studies to determine practical applicability in environmental monitoring.