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CTLA-4: a promising immunosuppressive immune checkpoint in prostate cancer therapy | Synapse
March 3, 2026
CTLA-4: a promising immunosuppressive immune checkpoint in prostate cancer therapy
NY
Nada Khairi Younis
AA
Ali Fawzi Al-Hussainy
SJ
S. Renuka Jyothi
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Key Points
CTLA-4 plays a vital role in regulating immune response, potentially impacting prostate cancer outcomes.
Recent findings indicate enhanced therapeutic effects when targeting CTLA-4 in various prostate cancer models.
Observational analysis of clinical trials shows improved patient responses to CTLA-4 blockade in prostate cancer therapy.
These results highlight the potential of CTLA-4 as a novel therapeutic target in prostate cancer treatment.
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Younis et al. (Sun,) studied this question.
synapsesocial.com/papers/69a76559badf0bb9e87d8cb6
https://doi.org/https://doi.org/10.1007/s12094-025-04213-4