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March 3, 2026
Identification of repopulated microglia-associated genes in microglia depleted/repopulated mice after spinal cord injury
SX
Shiyuan Xue
DH
Die Hu
LL
Liping Li
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Key Points
Microglia-associated genes were identified in repopulated mice after spinal cord injury, indicating their role in recovery.
Specifically, 18 distinct genes were found to be significantly altered during the repopulation process.
Analysis focused on genetic expression patterns following injury in microglia-depleted and repopulated mice.
The findings underscore the importance of microglia in neuroinflammation and healing post-injury.
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Identification of repopulated microglia-associated genes in microglia depleted/repopulated mice after spinal cord injury | Synapse
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Xue et al. (Sun,) studied this question.
synapsesocial.com/papers/69a76587badf0bb9e87d96fa
https://doi.org/https://doi.org/10.1016/j.brainres.2026.150189