Evidence-based extension of reagent shelf-life beyond expiry using patient-based moving averages, westgard sigma rules, and CLSI EP25

Key Points

• Reagent stability assessment can extend beyond expiry dates using a systematic approach, optimizing patient-based moving averages.
• Utilizing Westgard sigma rules and EP25 leads to significant improvements in detection performance, enhancing quality control procedures.
• Assessment involves simulation-optimized moving averages, integrating real patient data for more accurate results in laboratory settings.
• The framework supports cost-effective decisions regarding reagent reuse, ensuring reliability in laboratory testing procedures.